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Pragmatic trials are trials designed to provide information for the practice of clinical trials in real life. They are often characterized by a focus on the practical aspects of study design, such as the recruitment process and consent in adherence, as well as the use of routinely available equipment.
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While Pragmatic Play is known for its slot machines, it also offers table games such as Bitcoin baccarat and Roulette. They offer more than dozen licensed games, and their software has a reputation as secure and reliable. Their games are available in a variety of languages and offer a range of betting options including live dealer tables.
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Pragmatic, a software company, offers a variety of casino games on online gambling platforms. Pragmatic's iGaming software is used by the top operators as well as casinos that are located in the land. The company offers front-end website design tools, analysis and marketing, promotions security payment systems, 프라그마틱 플레이 customer service and bug-reporting. The company also offers a safe environment with high-quality graphics, games and security.
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The latest release from the company Gates of Olympus takes players to the world of the ancient Greek gods and goddesses, where Zeus is in charge of the action. This high-volatility slot game comes with a Pay Anywhere feature that awards players with winnings when they land eight or more matching symbols anywhere on the reels. This game also features the Free Spins bonus with multipliers up to 500x the bet.
Another example of a pragmatic trial is the Home Blood Pressure Management (HBPM) study, which utilized different investigators and participants from different geographic areas. This type of heterogeneity, that is crucial for pragmatic trials to be valid and to reduce bias in the results is also essential. Too much heterogeneity, however could cause issues with the trial design.
Pragmatic Play, one of the major players in the live casino market offers various classic table games, including Blackjack and Roulette. The live studios of the company in Romania and Malta offer customers an authentic experience in gambling as well a full variety of betting options via virtual. The company also has several game shows which make online gambling fun and interactive. Some of these shows are hosted live, while others include famous people from the industry.
Mobile compatibility
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In addition to their mobile-friendly slot machines, Pragmatic Play also offers tables games and live dealer casinos. The company is licensed by various regulatory bodies such as Malta Gaming Authority and UK Gambling Commission. The games of the company are secured with high-end encryption and its security staff is available to assist players with any issues.
Pragmatic Play's slot games are very popular with newbies and seasoned players. They feature modern graphics as well as traditional themes. They offer a range of paylines and bonus rounds, and many offer progressive jackpots. They are not volatile, which means you can have a long gaming experience.
Pragmatic Play offers a large variety of games that you can play for free before you decide whether you want to purchase them. These games are made to work on all types of devices including tablets, desktops and smartphones. They can be played anywhere that you connect to the internet. They are easy-to-navigate. Some Pragmatic Play sites even allow players to test their skills on the go using an exercise mode. This allows you to learn about game rules and features before playing for real money.
Legality
Pragmatic Play has gained a reputation for offering top-quality games and an outstanding user experience. Its software is designed to work on mobile devices and is compatible with different languages. It has established itself as one of the leading gaming platforms in the casino industry despite its relative youth. The latest releases include Wolves, a 5-reel video slot that has a healthy RTP and stunning graphics. Its other notable titles are Wolf Gold and Chilli Heat.
Pragmatic trials aim to mimic real-world situations and have the highest external validity. They are usually requested by practitioners and policymakers to help guide their decisions. They can be used to determine the cause-effect relationship of an intervention with its outcomes. However, they should not be used as a substitute for explanation trials.
The pragmatism concept is controversial, and there are concerns about whether pragmatic trials should replace or complement them. Schwartz and Lellouch1 proposed a distinction between explanatory studies, which prove the validity of a physiological or clinical hypothesis, and pragmatic trials, that inform the decision-making process for policy and practice. They also suggested a framework for pragmatic trials, called PRECIS.2 This tool attempted to define the features of a pragmatic trial, including recruitment, design and delivery of the intervention, as well as monitoring.
The number of pragmatic trials is growing. A recent Medline search using the terms naturalistic and pragmatic, limited to randomized controlled trials (RCTs) produced 34 articles, shown in red in Figure 2. This is an indication that the health sciences community is becoming more acquaint to the issue of pragmatism. It is important to note that the majority were conducted in primary-care settings.