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Studies designed to provide insight into clinical practice in the real world are known as pragmatic trials. They are typically described as a focus on the practical aspects of study design which include the recruitment and consent process, as well as adherence and the use of routinely available equipment.

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Another example of a pragmatic trial is the Home Blood Pressure Management (HBPM) study, which employed different investigators and included participants from different geographic areas. This type of heterogeneity, that is crucial for a pragmatic trial to be valid and to reduce bias in the results, is also necessary. However too much heterogeneity could cause problems with the design of the trial.

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The purpose of pragmatic trials is to mimic real-life scenarios and gain maximum validity externally. They are typically commissioned by practitioners and policy makers to inform their decision making. They are also a good method to determine the causality between an intervention and its results. However, they should not be used as a substitute for explanation studies.

The concept of pragmatism is controversial, and there are doubts about whether pragmatic trials should be used to replace explanatory trials or complement them. Schwartz and Lellouch1 suggested a distinction between explanatory trials, which validate the validity of a clinical or physiological hypothesis as well as pragmatic trials, which inform policy and practice decisions. They also proposed a framework called PRECIS for pragmatic trials.2 This tool attempted to define the characteristics of a practical study, including recruitment, design, implementation of the intervention and follow-up.

The number of pragmatic trials is growing. A recent Medline search using the keywords pragmatic and naturalistic, restricted to controlled trials randomized to control (RCTs) produced 34 articles, 프라그마틱 무료 슬롯버프 슬롯 하는법 (Pragmatic-Kr10864.Bleepblogs.Com) shown in red in Figure 2. This is a sign that the health science community is becoming increasingly sensitized to the subject of pragmatism. It is important to note, however, that the majority were conducted in primary care settings.